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Most men who use finasteride do very well with between 80-90% success rates for nearly all ages of men.

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Since these drugs inhibit the enzyme 5-alpha reductase, the testosterone that would normally be converted into DHT by this enzyme is not so converted.

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However, unlike finasteride, which only inhibits the Type II form of the enzyme, dutasteride inhibits both the Type I and Type II forms of the 5 alpha-reductase enzyme.

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Dutasteride and tamsulosin hydrochloride is contraindicated for use in pediatric patients.

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Avodart (dutasteride) prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body.

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Herein we detail the use of the 5α-reductase inhibitor dutasteride and the α1-adrenergic antagonist tamsulosin, and review the role of combination therapy in the medical treatment of LUTS caused by prostatic enlargement.

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Additionally, the MTOPS trial used the type-2 5α-reductase inhibitor finasteride whereas the CombAT study assesses the results of treatment using the dual 5α-reductase inhibitor dutasteride.

Do NOT take Soriatane if you are allergic to acitretin, the active ingredient in Soriatane, to any of the other ingredients in Soriatane (see the end of this Medication Guide for a list of all the ingredients in Soriatane), or to any medicines that are like Soriatane.

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